How does Mounjaro™ (tirzepatide) work for weight loss?
Mounjaro (tirzepatide) works by mimicking the action of two different gut hormones. When blood sugar rises after eating, the drug stimulates the body to produce more insulin, which lowers blood sugar. It also slows down the movement of food from the stomach, making people feel fuller for longer. When used along with healthy eating and exercise, overweight adults who may also have high blood pressure, diabetes, or high cholesterol typically see significant improvements across all health markers.
What is Mounjaro (tirzepatide)?
Mounjaro/Tirzepatide is a once-weekly GIP (glucose-dependent insulinotropic polypeptide) receptor and GLP-1 (glucagon-like peptide-1) receptor agonist. Tirzepatide is a single molecule that activates the body’s receptors for GIP and GLP-1, which are natural incretin hormones. Both GIP and GLP-1 receptors are found in areas of the human brain important for appetite regulation. Tirzepatide has been shown to decrease food intake and modulate fat utilization. Tirzepatide is in phase 3 development for adults with obesity, or overweight with weight-related comorbidity. Tirzepatide was approved as Mounjaro® (tirzepatide) by the FDA on May 13, 2022. Mounjarobelongs to a group of medications that was originally developed to treat diabetes and act on the GLP-1 receptor in the body, similar to Ozempic/Wegovy (semaglutide). However, Mounjaro also activates the GIP receptor, which makes it more effective than Ozempic/Wegovy.
What the program includes
- Consultation (virtual or in-person)
- Medication shipped monthly to your home with syringes and alcohol wipes
- Regular check-ins with your practitioner to manage your care and adjust medication as needed
- Injection training
- Optional in-office injections (prior to receiving medication)
- Lab monitoring
Weight loss, decreased appetite, decreased cravings, clothes fit better, less food intake and satiated longer, able to stop eating when full and don’t overeat, increased energy, elevated mood, and more!
How much weight can I lose?
In the SURMOUNT-1 and 2 trials (72 weeks), results showed an overall average weight loss of 20% for all participants and over 25% for a third of participants.
- Type 1 Diabetes
- Decreased kidney function
- Diabetic retinopathy, a type of damage to the eye from diabetes
- Disease of the gallbladder
- Family history of medullary thyroid carcinoma
- Medullary thyroid cancer
- Multiple endocrine neoplasia type 2
- Pregnant or breastfeeding
- Stomach muscle paralysis and decreased function
Benefits of weight loss
From reproductive function to memory and mood, excess weight compromises almost every aspect of health. Debilitating and deadly diseases associated with obesity include diabetes, heart disease, and certain types of cancer. A variety of mechanisms contribute to this, some as simple as mechanical stress caused by additional weight, while others involve changes in hormones and metabolism. The health and quality of life in obese individual are negatively affected by obesity, as are the world’s healthcare costs and systems.
Does taking Mounjaro (Tirzepatide) cause any side effects?
For a complete list of possible side effects and other important medical information, visit the Mounjaro™ website. The most common side effects include:
- Abdominal pain
- Decreased appetite
How is Mounjaro (Tirzepatide) taken?
A self-administered injection once per week. Prescriptions are for 4 weeks, and each month the tolerance to the medication and the current dose is assessed. The dose is adjusted depending on effect and possible side effects.
Lab testing and monitoring
An initial set of labs are is needed at the start of the program. You can order through your doctor or schedule a lab test appointment at Any Lab Test Now (located in Plymouth and Lakeville) and request the Annual Check-up Panel test, which includes the following. Bring your lab results to your first appointment.
- Complete Blood Count (CBC)
- Cholesterol Lipid with Ratio (Lipids Panel)
- Thyroid Stimulating Hormone (TSH)
- Comprehensive Metabolic Panel (CMP)
- Hemoglobin A1c (HbA1C)
Do I need to watch my diet and exercise while taking Mounjaro (Tirzepatide)?
Absolutely! Mounjaro (Tirzepatide) helps you lose weight and stick to healthy habits, but it does not cause weight loss by itself. If you want to sustain your body weight reduction, you must use it with other strategies that support metabolic health, such as dietary changes, exercise, and other healthy lifestyle changes.
Please contact us in one of the following ways to schedule an appointment.
- Book online
- Phone: 952-212-1268
- Text: 952-522-5868
- Request appointment
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